EMBL-EBI | Chemical Biology | ChEBI

Example searches: iron*, InChI=1S/CH4O/c1-2/h2H,1H3, caffeine | Advanced Search

CHEBI:76023 - thioflavine T

ChEBI IDCHEBI:76023
ChEBI Namethioflavine T
Stars
DefinitionAn organic chloride salt having 2-[4-(dimethylamino)phenyl]-3,6-dimethyl-1,3-benzothiazol-3-ium as the counterion. It is widely used to visualise and quantify the presence of amyloids, both in vitro and in vivo.
Secondary ChEBI IDCHEBI:88013
Last Modified28 October 2021
SubmitterMargaret Duesbury, Steve
DownloadsMolfile
FormulaC17H19N2S.Cl
Net Charge0
Average Mass318.873
Monoisotopic Mass318.09575
SMILESCc1ccc2c(c1)sc(-c1ccc(N(C)C)cc1)[n+]2C.[Cl-]
InChIInChI=1S/C17H19N2S.ClH/c1-12-5-10-15-16(11-12)20-17(19(15)4)13-6-8-14(9-7-13)18(2)3;/h5-11H,1-4H3;1H/q+1;/p-1
InChIKeyJADVWWSKYZXRGX-UHFFFAOYSA-M
Wikipedia
Roles Classification
Applications:
histological dye  A dye used in microscopic or electron microscopic examination of cells and tissues to give contrast and to highlight particular features of interest, such as nuclei and cytoplasm.
fluorochrome  A fluorescent dye used to stain biological specimens.
geroprotector  Any compound that supports healthy aging, slows the biological aging process, or extends lifespan.
ChEBI Ontology
Outgoing Relation(s)
thioflavine T (CHEBI:76023) has part thioflavin T cation (CHEBI:76034)
thioflavine T (CHEBI:76023) has role fluorochrome (CHEBI:51217)
thioflavine T (CHEBI:76023) has role geroprotector (CHEBI:176497)
thioflavine T (CHEBI:76023) has role histological dye (CHEBI:77178)
thioflavine T (CHEBI:76023) is a organic chloride salt (CHEBI:36094)
IUPAC Name 
2-[4-(dimethylamino)phenyl]-3,6-dimethyl-1,3-benzothiazol-3-ium chloride
Synonyms  Source
ThTSUBMITTER
C.I. 49005ChEBI
basic yellow 1ChEBI
C.I. Basic Yellow 1ChemIDplus
2-(4-(Dimethylamino)phenyl)-3,6-dimethylbenzothiazolium chlorideChemIDplus
Thioflavin TChemIDplus
Manual XrefsDatabases
WO2007011834Patent
WO2006006172Patent
Thioflavin_TWikipedia
Registry NumbersSources
Reaxys:3922452Reaxys
CAS:2390-54-7ChemIDplus
Citations