EMBL-EBI | Chemical Biology | ChEBI

Example searches: iron*, InChI=1S/CH4O/c1-2/h2H,1H3, caffeine | Advanced Search

CHEBI:75984 - flecainide

ChEBI IDCHEBI:75984
ChEBI Nameflecainide
Stars
DefinitionA monocarboxylic acid amide obtained by formal condensation of the carboxy group of 2,5-bis(2,2,2-trifluoroethoxy)benzoic acid with the primary amino group of piperidin-2-ylmethylamine. An antiarrhythmic agent used (in the form of its acetate salt) to prevent and treat tachyarrhythmia (abnormal fast rhythm of the heart).
Secondary ChEBI IDCHEBI:5090
Last Modified22 February 2017
DownloadsMolfile
FormulaC17H20F6N2O3
Net Charge0
Average Mass414.346
Monoisotopic Mass414.13781
SMILESO=C(NCC1CCCCN1)c1cc(OCC(F)(F)F)ccc1OCC(F)(F)F
InChIInChI=1S/C17H20F6N2O3/c18-16(19,20)9-27-12-4-5-14(28-10-17(21,22)23)13(7-12)15(26)25-8-11-3-1-2-6-24-11/h4-5,7,11,24H,1-3,6,8-10H2,(H,25,26)
InChIKeyDJBNUMBKLMJRSA-UHFFFAOYSA-N
Wikipedia
Roles Classification
Application:
anti-arrhythmia drug  A drug used for the treatment or prevention of cardiac arrhythmias. Anti-arrhythmia drugs may affect the polarisation-repolarisation phase of the action potential, its excitability or refractoriness, or impulse conduction or membrane responsiveness within cardiac fibres.
ChEBI Ontology
Outgoing Relation(s)
flecainide (CHEBI:75984) has role anti-arrhythmia drug (CHEBI:38070)
flecainide (CHEBI:75984) is a aromatic ether (CHEBI:35618)
flecainide (CHEBI:75984) is a monocarboxylic acid amide (CHEBI:29347)
flecainide (CHEBI:75984) is a organofluorine compound (CHEBI:37143)
flecainide (CHEBI:75984) is a piperidines (CHEBI:26151)
flecainide (CHEBI:75984) is conjugate base of flecainide(1+) (CHEBI:76033)
Incoming Relation(s)
flecainide(1+) (CHEBI:76033) is conjugate acid of flecainide (CHEBI:75984)
IUPAC Name 
N-(piperidin-2-ylmethyl)-2,5-bis(2,2,2-trifluoroethoxy)benzamide
INNs  Source
flecainideKEGG DRUG
flecainidaDrugBank
flecainidumDrugBank
flécaïnideWHO MedNet
Synonyms  Source
(±)-flecainideChemIDplus
CCRIS 313ChemIDplus
N-(2-Piperidinylmethyl)-2,5-bis(2,2,2-trifluoroethoxy)benzamideChemIDplus
FlecaineChemIDplus
Manual XrefsDatabases
C07001KEGG COMPOUND
D07962KEGG DRUG
DB01195DrugBank
HMDB0015326HMDB
FlecainideWikipedia
LSM-1297LINCS
1176DrugCentral
Registry NumbersSources
Reaxys:500093Reaxys
CAS:54143-55-4KEGG COMPOUND
CAS:54143-55-4ChemIDplus
Citations