gamcemetinib (CHEBI:759283)

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CHEBI:759283 - gamcemetinib

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ChEBI ID	CHEBI:759283
ChEBI Name	gamcemetinib
Stars
Last Modified	30 June 2026
Submitter	ChEMBL
Downloads	Molfile

Formula	C22H20ClN5O3S
Net Charge	0
Average Mass	469.954
Monoisotopic Mass	469.09754
SMILES	CCOCc1cnc(Cl)nc1Oc1ccc2c(ccc3sc4c(c32)NC[C@@H](C)NC4=O)n1
InChI	InChI=1S/C22H20ClN5O3S/c1-3-30-10-12-9-25-22(23)28-21(12)31-16-7-4-13-14(27-16)5-6-15-17(13)18-19(32-15)20(29)26-11(2)8-24-18/h4-7,9,11,24H,3,8,10H2,1-2H3,(H,26,29)/t11-/m1/s1
InChIKey	PYOQIOLRFIRRSO-LLVKDONJSA-N

Roles Classification

antirheumatic drug A drug used to treat rheumatoid arthritis.

anti-inflammatory agent Any compound that has anti-inflammatory effects.

ChEBI Ontology

Outgoing Relation(s)
	gamcemetinib (CHEBI:759283) has role anti-inflammatory agent (CHEBI:67079)
	gamcemetinib (CHEBI:759283) has role antirheumatic drug (CHEBI:35842)
	gamcemetinib (CHEBI:759283) is a quinolone (CHEBI:23765)

INN	Source
gamcemetinib	WHO MedNet

Synonyms	Source
BMS-986371	ChEMBL
CC-99677	ChEMBL

Citations