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CHEBI:758682 - exarafenib

Default Structure
ChEBI IDCHEBI:758682
ChEBI Nameexarafenib
Stars
Last Modified30 June 2026
SubmitterChEMBL
DownloadsMolfile
FormulaC26H34F3N5O3
Net Charge0
Average Mass521.584
Monoisotopic Mass521.26137
SMILESCc1ccc(NC(=O)N2CC[C@@H](CC(F)(F)F)C2)cc1-c1cc(N[C@H](C)CO)nc(N2CCOCC2)c1
InChIInChI=1S/C26H34F3N5O3/c1-17-3-4-21(31-25(36)34-6-5-19(15-34)14-26(27,28)29)13-22(17)20-11-23(30-18(2)16-35)32-24(12-20)33-7-9-37-10-8-33/h3-4,11-13,18-19,35H,5-10,14-16H2,1-2H3,(H,30,32)(H,31,36)/t18-,19+/m1/s1
InChIKeyGZMYLSJUNSCMTD-MOPGFXCFSA-N
Roles Classification
Application:
antineoplastic agent  A substance that inhibits or prevents the proliferation of neoplasms.
ChEBI Ontology
Outgoing Relation(s)
exarafenib (CHEBI:758682) has role antineoplastic agent (CHEBI:35610)
exarafenib (CHEBI:758682) is a ureas (CHEBI:47857)
INN  Source
exarafenibWHO MedNet
Synonym  Source
KIN-2787 FREE BASEChEMBL
Citations