EMBL-EBI | Chemical Biology | ChEBI
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| Formula | C17H17ClN6O2 |
| Net Charge | 0 |
| Average Mass | 372.816 |
| Monoisotopic Mass | 372.11015 |
| SMILES | CN(C)Cc1nc(-c2ncn3c2CN(C)C(=O)c2c(Cl)cccc2-3)no1 |
| InChI | InChI=1S/C17H17ClN6O2/c1-22(2)8-13-20-16(21-26-13)15-12-7-23(3)17(25)14-10(18)5-4-6-11(14)24(12)9-19-15/h4-6,9H,7-8H2,1-3H3 |
| InChIKey | JCYLWUVDHLVGER-UHFFFAOYSA-N |
| Roles Classification |
|---|
| Biological Role: | GABA modulator A substance that does not act as agonist or antagonist but does affect the gamma-aminobutyric acid receptor-ionophore complex. GABA-A receptors appear to have at least three allosteric sites at which modulators act: a site at which benzodiazepines act by increasing the opening frequency of gamma-aminobutyric acid-activated chloride channels; a site at which barbiturates act to prolong the duration of channel opening; and a site at which some steroids may act. |
| Application: | GABA modulator A substance that does not act as agonist or antagonist but does affect the gamma-aminobutyric acid receptor-ionophore complex. GABA-A receptors appear to have at least three allosteric sites at which modulators act: a site at which benzodiazepines act by increasing the opening frequency of gamma-aminobutyric acid-activated chloride channels; a site at which barbiturates act to prolong the duration of channel opening; and a site at which some steroids may act. |
| ChEBI Ontology |
|---|
| Outgoing Relation(s) |
| dimdazenil (CHEBI:758679) is a benzodiazepine (CHEBI:22720) |
| INN | Source |
|---|---|
| dimdazenil | WHO MedNet |
| Synonyms | Source |
|---|---|
| EVT-201 | ChEMBL |
| EVT201 | ChEMBL |