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CHEBI:757781 - gefapixant citrate

Default Structure
ChEBI IDCHEBI:757781
ChEBI Namegefapixant citrate
Stars
Last Modified30 June 2026
SubmitterChEMBL
DownloadsMolfile
FormulaC6H8O7.C14H19N5O4S
Net Charge0
Average Mass545.527
Monoisotopic Mass545.14278
SMILESCOc1cc(C(C)C)c(Oc2cnc(N)nc2N)cc1S(N)(=O)=O.O=C(O)CC(O)(CC(=O)O)C(=O)O
InChIInChI=1S/C14H19N5O4S.C6H8O7/c1-7(2)8-4-10(22-3)12(24(17,20)21)5-9(8)23-11-6-18-14(16)19-13(11)15;7-3(8)1-6(13,5(11)12)2-4(9)10/h4-7H,1-3H3,(H2,17,20,21)(H4,15,16,18,19);13H,1-2H2,(H,7,8)(H,9,10)(H,11,12)
InChIKeyAIJVJYUOMCRFOE-UHFFFAOYSA-N
Roles Classification
Application:
antitussive  An agent that suppresses cough. Antitussives have a central or a peripheral action on the cough reflex, or a combination of both. Compare with expectorants, which are considered to increase the volume of secretions in the respiratory tract, so facilitating their removal by ciliary action and coughing, and mucolytics, which decrease the viscosity of mucus, facilitating its removal by ciliary action and expectoration.
ChEBI Ontology
Outgoing Relation(s)
gefapixant citrate (CHEBI:757781) has role antitussive (CHEBI:51177)
gefapixant citrate (CHEBI:757781) is a aromatic ether (CHEBI:35618)
Synonyms  Source
AF-219 CITRATEChEMBL
Gefapixant citrateChEMBL
MK-7264ChEMBL
MK7264ChEMBL
MK-7264 CITRATEChEMBL
MK7264 CITRATEChEMBL
Brand Name  Source
LyfnuaChEMBL