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CHEBI:757666 - plixorafenib

Default Structure
ChEBI IDCHEBI:757666
ChEBI Nameplixorafenib
Stars
Last Modified30 June 2026
SubmitterChEMBL
DownloadsMolfile
FormulaC25H21F3N6O3S
Net Charge0
Average Mass542.543
Monoisotopic Mass542.13479
SMILESO=C(c1c(F)ccc(NS(=O)(=O)N2CC[C@@H](F)C2)c1F)c1cnc2ncc(-c3cnc(C4CC4)nc3)cc12
InChIInChI=1S/C25H21F3N6O3S/c26-16-5-6-34(12-16)38(36,37)33-20-4-3-19(27)21(22(20)28)23(35)18-11-32-25-17(18)7-14(8-31-25)15-9-29-24(30-10-15)13-1-2-13/h3-4,7-11,13,16,33H,1-2,5-6,12H2,(H,31,32)/t16-/m1/s1
InChIKeyYYACLQUDUDXAPA-MRXNPFEDSA-N
Roles Classification
Application:
antineoplastic agent  A substance that inhibits or prevents the proliferation of neoplasms.
ChEBI Ontology
Outgoing Relation(s)
plixorafenib (CHEBI:757666) has role antineoplastic agent (CHEBI:35610)
plixorafenib (CHEBI:757666) is a aromatic ketone (CHEBI:76224)
INN  Source
plixorafenibWHO MedNet
Synonyms  Source
FORE-8394ChEMBL
FORE8394ChEMBL
Plx 8394ChEMBL
Plx-8394ChEMBL
PLX8394ChEMBL