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CHEBI:757017 - gsk-2018682

Default Structure
ChEBI IDCHEBI:757017
ChEBI Namegsk-2018682
Stars
Last Modified30 June 2026
SubmitterChEMBL
DownloadsMolfile
FormulaC22H21ClN4O4
Net Charge0
Average Mass440.887
Monoisotopic Mass440.12513
SMILESCC(C)Oc1ncc(-c2nc(-c3cccc4c3ccn4CCCC(=O)O)no2)cc1Cl
InChIInChI=1S/C22H21ClN4O4/c1-13(2)30-22-17(23)11-14(12-24-22)21-25-20(26-31-21)16-5-3-6-18-15(16)8-10-27(18)9-4-7-19(28)29/h3,5-6,8,10-13H,4,7,9H2,1-2H3,(H,28,29)
InChIKeyNFIGDBFIDKDNIG-UHFFFAOYSA-N
Roles Classification
Biological Role:
immunosuppressive agent  An agent that suppresses immune function by one of several mechanisms of action. Classical cytotoxic immunosuppressants act by inhibiting DNA synthesis. Others may act through activation of T-cells or by inhibiting the activation of helper cells. In addition, an immunosuppressive agent is a role played by a compound which is exhibited by a capability to diminish the extent and/or voracity of an immune response.
Application:
immunosuppressive agent  An agent that suppresses immune function by one of several mechanisms of action. Classical cytotoxic immunosuppressants act by inhibiting DNA synthesis. Others may act through activation of T-cells or by inhibiting the activation of helper cells. In addition, an immunosuppressive agent is a role played by a compound which is exhibited by a capability to diminish the extent and/or voracity of an immune response.
ChEBI Ontology
Outgoing Relation(s)
gsk-2018682 (CHEBI:757017) has role immunosuppressive agent (CHEBI:35705)
gsk-2018682 (CHEBI:757017) is a indoles (CHEBI:24828)
Synonyms  Source
Gsk-2018682ChEMBL
GSK2018682ChEMBL
Citations