pexmetinib (CHEBI:756558)

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CHEBI:756558 - pexmetinib

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ChEBI ID	CHEBI:756558
ChEBI Name	pexmetinib
Stars
Last Modified	29 June 2026
Submitter	ChEMBL
Downloads	Molfile

Formula	C31H33FN6O3
Net Charge	0
Average Mass	556.642
Monoisotopic Mass	556.25982
SMILES	Cc1ccc(-n2nc(C(C)(C)C)cc2NC(=O)NCc2cc(F)ccc2Oc2ccc3c(cnn3CCO)c2)cc1
InChI	InChI=1S/C31H33FN6O3/c1-20-5-8-24(9-6-20)38-29(17-28(36-38)31(2,3)4)35-30(40)33-18-22-15-23(32)7-12-27(22)41-25-10-11-26-21(16-25)19-34-37(26)13-14-39/h5-12,15-17,19,39H,13-14,18H2,1-4H3,(H2,33,35,40)
InChIKey	LNMRSSIMGCDUTP-UHFFFAOYSA-N

Roles Classification

antineoplastic agent A substance that inhibits or prevents the proliferation of neoplasms.

ChEBI Ontology

Outgoing Relation(s)
	pexmetinib (CHEBI:756558) has role antineoplastic agent (CHEBI:35610)
	pexmetinib (CHEBI:756558) is a pyrazoles (CHEBI:26410)
	pexmetinib (CHEBI:756558) is a ring assembly (CHEBI:36820)

INN	Source
pexmetinib	WHO MedNet

Synonym	Source
ARRY-614	ChEMBL

Citations