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CHEBI:756454 - mavelertinib

Default Structure
ChEBI IDCHEBI:756454
ChEBI Namemavelertinib
Stars
Last Modified29 June 2026
SubmitterChEMBL
DownloadsMolfile
FormulaC18H22FN9O2
Net Charge0
Average Mass415.433
Monoisotopic Mass415.18805
SMILESC=CC(=O)N[C@@H]1CN(c2nc(Nc3cn(C)nc3OC)c3ncn(C)c3n2)C[C@H]1F
InChIInChI=1S/C18H22FN9O2/c1-5-13(29)21-11-8-28(6-10(11)19)18-23-15(14-16(24-18)26(2)9-20-14)22-12-7-27(3)25-17(12)30-4/h5,7,9-11H,1,6,8H2,2-4H3,(H,21,29)(H,22,23,24)/t10-,11-/m1/s1
InChIKeyJYIUNVOCEFIUIU-GHMZBOCLSA-N
Roles Classification
Application:
antineoplastic agent  A substance that inhibits or prevents the proliferation of neoplasms.
ChEBI Ontology
Outgoing Relation(s)
mavelertinib (CHEBI:756454) has role antineoplastic agent (CHEBI:35610)
mavelertinib (CHEBI:756454) is a purines (CHEBI:26401)
INN  Source
mavelertinibWHO MedNet
Synonyms  Source
Egfr t790m inhibitor pf-06747775ChEMBL
PF-06747775ChEMBL
Citations