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CHEBI:755996 - zanubrutinib

Default Structure
ChEBI IDCHEBI:755996
ChEBI Namezanubrutinib
Stars
Last Modified29 June 2026
SubmitterChEMBL
DownloadsMolfile
FormulaC27H29N5O3
Net Charge0
Average Mass471.561
Monoisotopic Mass471.22704
SMILESC=CC(=O)N1CCC([C@@H]2CCNc3c(C(N)=O)c(-c4ccc(Oc5ccccc5)cc4)nn32)CC1
InChIInChI=1S/C27H29N5O3/c1-2-23(33)31-16-13-18(14-17-31)22-12-15-29-27-24(26(28)34)25(30-32(22)27)19-8-10-21(11-9-19)35-20-6-4-3-5-7-20/h2-11,18,22,29H,1,12-17H2,(H2,28,34)/t22-/m0/s1
InChIKeyRNOAOAWBMHREKO-QFIPXVFZSA-N
Roles Classification
Biological Roles:
antiviral agent  A substance that destroys or inhibits replication of viruses.
immunosuppressive agent  An agent that suppresses immune function by one of several mechanisms of action. Classical cytotoxic immunosuppressants act by inhibiting DNA synthesis. Others may act through activation of T-cells or by inhibiting the activation of helper cells. In addition, an immunosuppressive agent is a role played by a compound which is exhibited by a capability to diminish the extent and/or voracity of an immune response.
Applications:
renoprotective agent  Any compound that is able to prevent damage to the kidneys.
anti-inflammatory agent  Any compound that has anti-inflammatory effects.
antineoplastic agent  A substance that inhibits or prevents the proliferation of neoplasms.
immunosuppressive agent  An agent that suppresses immune function by one of several mechanisms of action. Classical cytotoxic immunosuppressants act by inhibiting DNA synthesis. Others may act through activation of T-cells or by inhibiting the activation of helper cells. In addition, an immunosuppressive agent is a role played by a compound which is exhibited by a capability to diminish the extent and/or voracity of an immune response.
anti-anaemic agent  A compound which increases either the number of red cells or the amount of haemoglobin in the blood.
ChEBI Ontology
Outgoing Relation(s)
zanubrutinib (CHEBI:755996) has role anti-anaemic agent (CHEBI:75835)
zanubrutinib (CHEBI:755996) has role anti-inflammatory agent (CHEBI:67079)
zanubrutinib (CHEBI:755996) has role antineoplastic agent (CHEBI:35610)
zanubrutinib (CHEBI:755996) has role antiviral agent (CHEBI:22587)
zanubrutinib (CHEBI:755996) has role immunosuppressive agent (CHEBI:35705)
zanubrutinib (CHEBI:755996) has role renoprotective agent (CHEBI:231911)
zanubrutinib (CHEBI:755996) is a aromatic ether (CHEBI:35618)
Synonyms  Source
BGB-3111ChEMBL
ZanubrutinibChEMBL
Brand Name  Source
BrukinsaChEMBL
Citations