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CHEBI:755964 - larotrectinib

Default Structure
ChEBI IDCHEBI:755964
ChEBI Namelarotrectinib
Stars
Last Modified29 June 2026
SubmitterChEMBL
DownloadsMolfile
FormulaC21H22F2N6O2
Net Charge0
Average Mass428.443
Monoisotopic Mass428.17723
SMILESO=C(Nc1cnn2ccc(N3CCC[C@@H]3c3cc(F)ccc3F)nc12)N1CC[C@H](O)C1
InChIInChI=1S/C21H22F2N6O2/c22-13-3-4-16(23)15(10-13)18-2-1-7-28(18)19-6-9-29-20(26-19)17(11-24-29)25-21(31)27-8-5-14(30)12-27/h3-4,6,9-11,14,18,30H,1-2,5,7-8,12H2,(H,25,31)/t14-,18+/m0/s1
InChIKeyNYNZQNWKBKUAII-KBXCAEBGSA-N
Roles Classification
Application:
antineoplastic agent  A substance that inhibits or prevents the proliferation of neoplasms.
ChEBI Ontology
Outgoing Relation(s)
larotrectinib (CHEBI:755964) has role antineoplastic agent (CHEBI:35610)
larotrectinib (CHEBI:755964) is a pyrrolidines (CHEBI:38260)
Synonyms  Source
ARRY-470ChEMBL
BAY-2757556ChEMBL
BAY2757556ChEMBL
LarotrectinibChEMBL
LOXO-101ChEMBL
Citations