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CHEBI:755680 - siremadlin

Default Structure
ChEBI IDCHEBI:755680
ChEBI Namesiremadlin
Stars
Last Modified29 June 2026
SubmitterChEMBL
DownloadsMolfile
FormulaC26H24Cl2N6O4
Net Charge0
Average Mass555.422
Monoisotopic Mass554.12361
SMILESCOc1ncc(-c2nc3c(n2C(C)C)[C@H](c2ccc(Cl)cc2)N(c2cc(Cl)cn(C)c2=O)C3=O)c(OC)n1
InChIInChI=1S/C26H24Cl2N6O4/c1-13(2)33-21-19(30-22(33)17-11-29-26(38-5)31-23(17)37-4)25(36)34(18-10-16(28)12-32(3)24(18)35)20(21)14-6-8-15(27)9-7-14/h6-13,20H,1-5H3/t20-/m0/s1
InChIKeyAGBSXNCBIWWLHD-FQEVSTJZSA-N
Roles Classification
Applications:
antineoplastic agent  A substance that inhibits or prevents the proliferation of neoplasms.
antifibrotic agent  Any agent which acts to reduce fibrosis.
ChEBI Ontology
Outgoing Relation(s)
siremadlin (CHEBI:755680) has role antifibrotic agent (CHEBI:233423)
siremadlin (CHEBI:755680) has role antineoplastic agent (CHEBI:35610)
siremadlin (CHEBI:755680) is a chloropyridine (CHEBI:39173)
INNs  Source
siremadlinWHO MedNet
siremadlinaWHO MedNet
siremadlineWHO MedNet
Synonyms  Source
Hdm 201ChEMBL
HDM-201ChEMBL
HDM201ChEMBL
NVP-HDM 201ChEMBL
Citations