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CHEBI:755587 - talfirastide
| Formula | C41H62N12O11 |
| Net Charge | 0 |
| Average Mass | 899.020 |
| Monoisotopic Mass | 898.46610 |
| SMILES | [H][C@@](NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@@H](NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](N)CC(=O)O)C(C)C)(C(=O)N[C@@H](Cc1cncn1)C(=O)N1CCC[C@H]1C(=O)O)[C@@H](C)CC |
| InChI | InChI=1S/C41H62N12O11/c1-5-22(4)33(38(61)50-29(17-24-19-45-20-47-24)39(62)53-15-7-9-30(53)40(63)64)52-36(59)28(16-23-10-12-25(54)13-11-23)49-37(60)32(21(2)3)51-35(58)27(8-6-14-46-41(43)44)48-34(57)26(42)18-31(55)56/h10-13,19-22,26-30,32-33,54H,5-9,14-18,42H2,1-4H3,(H,45,47)(H,48,57)(H,49,60)(H,50,61)(H,51,58)(H,52,59)(H,55,56)(H,63,64)(H4,43,44,46)/t22-,26-,27-,28-,29-,30-,32-,33-/m0/s1 |
| InChIKey | PVHLMTREZMEJCG-GDTLVBQBSA-N |
| Roles Classification |
|---|
| Chemical Role: | Bronsted base A molecular entity capable of accepting a hydron from a donor (Brønsted acid). |
| Biological Roles: | anticoronaviral agent Any antiviral agent which inhibits the activity of coronaviruses. anti-HIV agent An antiviral agent that destroys or inhibits the replication of the human immunodeficiency virus. anti-obesity agent Any substance which is used to reduce or control weight. antiviral agent A substance that destroys or inhibits replication of viruses. |
| Applications: | antihypertensive agent Any drug used in the treatment of acute or chronic vascular hypertension regardless of pharmacological mechanism. neuroprotective agent Any compound that can be used for the treatment of neurodegenerative disorders. geroprotector Any compound that supports healthy aging, slows the biological aging process, or extends lifespan. anti-inflammatory agent Any compound that has anti-inflammatory effects. antineoplastic agent A substance that inhibits or prevents the proliferation of neoplasms. cardiovascular drug A drug that affects the rate or intensity of cardiac contraction, blood vessel diameter or blood volume. |
| ChEBI Ontology |
|---|
| Outgoing Relation(s) |
| talfirastide (CHEBI:755587) has role anti-HIV agent (CHEBI:64946) |
| talfirastide (CHEBI:755587) has role anti-inflammatory agent (CHEBI:67079) |
| talfirastide (CHEBI:755587) has role anti-obesity agent (CHEBI:74518) |
| talfirastide (CHEBI:755587) has role anticoronaviral agent (CHEBI:149553) |
| talfirastide (CHEBI:755587) has role antihypertensive agent (CHEBI:35674) |
| talfirastide (CHEBI:755587) has role antineoplastic agent (CHEBI:35610) |
| talfirastide (CHEBI:755587) has role antiviral agent (CHEBI:22587) |
| talfirastide (CHEBI:755587) has role cardiovascular drug (CHEBI:35554) |
| talfirastide (CHEBI:755587) has role geroprotector (CHEBI:176497) |
| talfirastide (CHEBI:755587) has role neuroprotective agent (CHEBI:63726) |
| talfirastide (CHEBI:755587) is a polypeptide (CHEBI:15841) |
| INNs | Source |
|---|---|
| talfirastida | WHO MedNet |
| talfirastide | WHO MedNet |
| Synonyms | Source |
|---|---|
| 5-ile-angiotensin-(1-7) | ChEMBL |
| A(1-7) | ChEMBL |
| Ang-(1-7) | ChEMBL |
| Angiotensin 1-7 | ChEMBL |
| Angiotensin-(1-7) | ChEMBL |
| Angiotensin fragment 1-7 | ChEMBL |
| Brand Name | Source |
|---|---|
| Marstem | ChEMBL |