encorafenib (CHEBI:755294)

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CHEBI:755294 - encorafenib

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ChEBI ID	CHEBI:755294
ChEBI Name	encorafenib
Stars
Last Modified	29 June 2026
Submitter	ChEMBL
Downloads	Molfile

Formula	C22H27ClFN7O4S
Net Charge	0
Average Mass	540.021
Monoisotopic Mass	539.15178
SMILES	[H][C@](C)(CNc1nccc(-c2cn(C(C)C)nc2-c2cc(Cl)cc(NS(C)(=O)=O)c2F)n1)NC(=O)OC
InChI	InChI=1S/C22H27ClFN7O4S/c1-12(2)31-11-16(17-6-7-25-21(28-17)26-10-13(3)27-22(32)35-4)20(29-31)15-8-14(23)9-18(19(15)24)30-36(5,33)34/h6-9,11-13,30H,10H2,1-5H3,(H,27,32)(H,25,26,28)/t13-/m0/s1
InChIKey	CMJCXYNUCSMDBY-ZDUSSCGKSA-N

Roles Classification

antineoplastic agent A substance that inhibits or prevents the proliferation of neoplasms.

ChEBI Ontology

Outgoing Relation(s)
	encorafenib (CHEBI:755294) has role antineoplastic agent (CHEBI:35610)
	encorafenib (CHEBI:755294) is a pyrazoles (CHEBI:26410)
	encorafenib (CHEBI:755294) is a ring assembly (CHEBI:36820)

Synonyms	Source
Encorafenib	ChEMBL
Lgx-818	ChEMBL
Lgx818	ChEMBL
NVP-LGX818	ChEMBL
NVP-LGX-818-NXA	ChEMBL
NVP-LGX818-NXA	ChEMBL

Brand Name	Source
Braftovi	ChEMBL

Citations