uprosertib (CHEBI:755163)

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CHEBI:755163 - uprosertib

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ChEBI ID	CHEBI:755163
ChEBI Name	uprosertib
Stars
Last Modified	29 June 2026
Submitter	ChEMBL
Downloads	Molfile

Formula	C18H16Cl2F2N4O2
Net Charge	0
Average Mass	429.254
Monoisotopic Mass	428.06184
SMILES	Cn1ncc(Cl)c1-c1cc(C(=O)N[C@H](CN)Cc2ccc(F)c(F)c2)oc1Cl
InChI	InChI=1S/C18H16Cl2F2N4O2/c1-26-16(12(19)8-24-26)11-6-15(28-17(11)20)18(27)25-10(7-23)4-9-2-3-13(21)14(22)5-9/h2-3,5-6,8,10H,4,7,23H2,1H3,(H,25,27)/t10-/m0/s1
InChIKey	AXTAPYRUEKNRBA-JTQLQIEISA-N

Roles Classification

Chemical Roles:	Bronsted base A molecular entity capable of accepting a hydron from a donor (Brønsted acid). Bronsted base A molecular entity capable of accepting a hydron from a donor (Brønsted acid).
Applications:	antineoplastic agent A substance that inhibits or prevents the proliferation of neoplasms. central nervous system stimulant Any drug that enhances the activity of the central nervous system.

ChEBI Ontology

Outgoing Relation(s)
	uprosertib (CHEBI:755163) has role antineoplastic agent (CHEBI:35610)
	uprosertib (CHEBI:755163) is a amphetamines (CHEBI:35338)

INN	Source
uprosertib	WHO MedNet

Synonyms	Source
Akt inhibitor gsk-2141795	ChEMBL
Akt inhibitor gsk2141795	ChEMBL
Gsk-2141795	ChEMBL
GSK2141795	ChEMBL
GSK-2141795C	ChEMBL
GSK2141795C	ChEMBL

Citations