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CHEBI:755133 - navtemadlin

Default Structure
ChEBI IDCHEBI:755133
ChEBI Namenavtemadlin
Stars
Last Modified29 June 2026
SubmitterChEMBL
DownloadsMolfile
FormulaC28H35Cl2NO5S
Net Charge0
Average Mass568.563
Monoisotopic Mass567.16130
SMILESCC(C)[C@@H](CS(=O)(=O)C(C)C)N1C(=O)[C@@](C)(CC(=O)O)C[C@H](c2cccc(Cl)c2)[C@H]1c1ccc(Cl)cc1
InChIInChI=1S/C28H35Cl2NO5S/c1-17(2)24(16-37(35,36)18(3)4)31-26(19-9-11-21(29)12-10-19)23(20-7-6-8-22(30)13-20)14-28(5,27(31)34)15-25(32)33/h6-13,17-18,23-24,26H,14-16H2,1-5H3,(H,32,33)/t23-,24-,26-,28-/m1/s1
InChIKeyDRLCSJFKKILATL-YWCVFVGNSA-N
Roles Classification
Applications:
antineoplastic agent  A substance that inhibits or prevents the proliferation of neoplasms.
antifibrotic agent  Any agent which acts to reduce fibrosis.
ChEBI Ontology
Outgoing Relation(s)
navtemadlin (CHEBI:755133) has role antifibrotic agent (CHEBI:233423)
navtemadlin (CHEBI:755133) has role antineoplastic agent (CHEBI:35610)
navtemadlin (CHEBI:755133) is a stilbenoid (CHEBI:26776)
INN  Source
navtemadlinWHO MedNet
Synonyms  Source
AMG 232ChEMBL
AMG-232ChEMBL
KRT-232ChEMBL
Mdm2 inhibitor amg-232ChEMBL
Citations