EMBL-EBI | Chemical Biology | ChEBI
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CHEBI:754462 - iomazenil
| Formula | C15H14IN3O3 |
| Net Charge | 0 |
| Average Mass | 411.199 |
| Monoisotopic Mass | 411.00799 |
| SMILES | CCOC(=O)c1ncn2c1CN(C)C(=O)c1c(I)cccc1-2 |
| InChI | InChI=1S/C15H14IN3O3/c1-3-22-15(21)13-11-7-18(2)14(20)12-9(16)5-4-6-10(12)19(11)8-17-13/h4-6,8H,3,7H2,1-2H3 |
| InChIKey | FRIZVHMAECRUBR-UHFFFAOYSA-N |
| Roles Classification |
|---|
| Biological Role: | GABA modulator A substance that does not act as agonist or antagonist but does affect the gamma-aminobutyric acid receptor-ionophore complex. GABA-A receptors appear to have at least three allosteric sites at which modulators act: a site at which benzodiazepines act by increasing the opening frequency of gamma-aminobutyric acid-activated chloride channels; a site at which barbiturates act to prolong the duration of channel opening; and a site at which some steroids may act. |
| Applications: | antipsychotic agent Antipsychotic drugs are agents that control agitated psychotic behaviour, alleviate acute psychotic states, reduce psychotic symptoms, and exert a quieting effect. GABA modulator A substance that does not act as agonist or antagonist but does affect the gamma-aminobutyric acid receptor-ionophore complex. GABA-A receptors appear to have at least three allosteric sites at which modulators act: a site at which benzodiazepines act by increasing the opening frequency of gamma-aminobutyric acid-activated chloride channels; a site at which barbiturates act to prolong the duration of channel opening; and a site at which some steroids may act. |
| ChEBI Ontology |
|---|
| Outgoing Relation(s) |
| iomazenil (CHEBI:754462) has role antipsychotic agent (CHEBI:35476) |
| iomazenil (CHEBI:754462) is a benzodiazepine (CHEBI:22720) |
| Synonyms | Source |
|---|---|
| RO 16-0154 | ChEMBL |
| RO-16-0154 | ChEMBL |
| RO16-0154 | ChEMBL |