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CHEBI:754456 - vabicaserin

Default Structure
ChEBI IDCHEBI:754456
ChEBI Namevabicaserin
Stars
Last Modified29 June 2026
SubmitterChEMBL
DownloadsMolfile
FormulaC15H20N2
Net Charge0
Average Mass228.339
Monoisotopic Mass228.16265
SMILES[H][C@@]12CCC[C@]1([H])c1cccc3c1N(CCNC3)C2
InChIInChI=1S/C15H20N2/c1-3-11-9-16-7-8-17-10-12-4-2-5-13(12)14(6-1)15(11)17/h1,3,6,12-13,16H,2,4-5,7-10H2/t12-,13-/m0/s1
InChIKeyNPTIPEQJIDTVKR-STQMWFEESA-N
Roles Classification
Biological Role:
GABA modulator  A substance that does not act as agonist or antagonist but does affect the gamma-aminobutyric acid receptor-ionophore complex. GABA-A receptors appear to have at least three allosteric sites at which modulators act: a site at which benzodiazepines act by increasing the opening frequency of gamma-aminobutyric acid-activated chloride channels; a site at which barbiturates act to prolong the duration of channel opening; and a site at which some steroids may act.
Applications:
antipsychotic agent  Antipsychotic drugs are agents that control agitated psychotic behaviour, alleviate acute psychotic states, reduce psychotic symptoms, and exert a quieting effect.
GABA modulator  A substance that does not act as agonist or antagonist but does affect the gamma-aminobutyric acid receptor-ionophore complex. GABA-A receptors appear to have at least three allosteric sites at which modulators act: a site at which benzodiazepines act by increasing the opening frequency of gamma-aminobutyric acid-activated chloride channels; a site at which barbiturates act to prolong the duration of channel opening; and a site at which some steroids may act.
ChEBI Ontology
Outgoing Relation(s)
vabicaserin (CHEBI:754456) has role antipsychotic agent (CHEBI:35476)
vabicaserin (CHEBI:754456) is a benzodiazepine (CHEBI:22720)
INNs  Source
vabicaserinWHO MedNet
vabicaserinaWHO MedNet
vabicaserineWHO MedNet
Citations