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CHEBI:75399 - NU 1025

ChEBI IDCHEBI:75399
ChEBI NameNU 1025
Stars
DefinitionA member of the class of quinazolines that is quinazolin-4(1H)-one substituted by a hydroxy group at position 8 and a methyl group at position 2. It has been shown to exhibit inhibitory activity against poly(ADP-ribose) polymerase.
Last Modified25 February 2016
Submitternamrata
DownloadsMolfile
FormulaC9H8N2O2
Net Charge0
Average Mass176.175
Monoisotopic Mass176.05858
SMILESCc1nc(=O)c2cccc(O)c2n1
InChIInChI=1S/C9H8N2O2/c1-5-10-8-6(9(13)11-5)3-2-4-7(8)12/h2-4,12H,1H3,(H,10,11,13)
InChIKeyYJDAOHJWLUNFLX-UHFFFAOYSA-N
Roles Classification
Biological Role:
EC 2.4.2.30 (NAD(+) ADP-ribosyltransferase) inhibitor  An EC 2.4.2.* (pentosyltransferase) inhibitor that interferes with the action of a NAD+ ADP-ribosyltransferase (EC 2.4.2.30).
ChEBI Ontology
Outgoing Relation(s)
NU 1025 (CHEBI:75399) has role EC 2.4.2.30 (NAD+ ADP-ribosyltransferase) inhibitor (CHEBI:62913)
NU 1025 (CHEBI:75399) is a phenols (CHEBI:33853)
NU 1025 (CHEBI:75399) is a quinazolines (CHEBI:38530)
IUPAC Name 
8-hydroxy-2-methylquinazolin-4(1H)-one
Manual XrefsDatabases
DB02690DrugBank
LSM-4643LINCS
Registry NumbersSources
Reaxys:10249307Reaxys
CAS:90417-38-2ChemIDplus
Citations