EMBL-EBI | Chemical Biology | ChEBI
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| Formula | C17H13F3N2O2 |
| Net Charge | 0 |
| Average Mass | 334.297 |
| Monoisotopic Mass | 334.09291 |
| SMILES | CN1C(=O)CC(=O)N(c2ccccc2)c2cc(C(F)(F)F)ccc21 |
| InChI | InChI=1S/C17H13F3N2O2/c1-21-13-8-7-11(17(18,19)20)9-14(13)22(16(24)10-15(21)23)12-5-3-2-4-6-12/h2-9H,10H2,1H3 |
| InChIKey | DMNPCIKBNDKNTO-UHFFFAOYSA-N |
| Roles Classification |
|---|
| Biological Role: | GABA modulator A substance that does not act as agonist or antagonist but does affect the gamma-aminobutyric acid receptor-ionophore complex. GABA-A receptors appear to have at least three allosteric sites at which modulators act: a site at which benzodiazepines act by increasing the opening frequency of gamma-aminobutyric acid-activated chloride channels; a site at which barbiturates act to prolong the duration of channel opening; and a site at which some steroids may act. |
| Application: | GABA modulator A substance that does not act as agonist or antagonist but does affect the gamma-aminobutyric acid receptor-ionophore complex. GABA-A receptors appear to have at least three allosteric sites at which modulators act: a site at which benzodiazepines act by increasing the opening frequency of gamma-aminobutyric acid-activated chloride channels; a site at which barbiturates act to prolong the duration of channel opening; and a site at which some steroids may act. |
| ChEBI Ontology |
|---|
| Outgoing Relation(s) |
| triflubazam (CHEBI:752542) is a benzodiazepine (CHEBI:22720) |
| INN | Source |
|---|---|
| triflubazam | WHO MedNet |
| Synonyms | Source |
|---|---|
| ORF-8063 | ChEMBL |
| WE-352 | ChEMBL |
| WE352 | ChEMBL |