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CHEBI:752466 - lofendazam

Default Structure
ChEBI IDCHEBI:752466
ChEBI Namelofendazam
Stars
Last Modified29 June 2026
SubmitterChEMBL
DownloadsMolfile
FormulaC15H13ClN2O
Net Charge0
Average Mass272.735
Monoisotopic Mass272.07164
SMILESO=C1CCNc2ccc(Cl)cc2N1c1ccccc1
InChIInChI=1S/C15H13ClN2O/c16-11-6-7-13-14(10-11)18(15(19)8-9-17-13)12-4-2-1-3-5-12/h1-7,10,17H,8-9H2
InChIKeyIUJQOUHDFKALCY-UHFFFAOYSA-N
Roles Classification
Biological Role:
GABA modulator  A substance that does not act as agonist or antagonist but does affect the gamma-aminobutyric acid receptor-ionophore complex. GABA-A receptors appear to have at least three allosteric sites at which modulators act: a site at which benzodiazepines act by increasing the opening frequency of gamma-aminobutyric acid-activated chloride channels; a site at which barbiturates act to prolong the duration of channel opening; and a site at which some steroids may act.
Application:
GABA modulator  A substance that does not act as agonist or antagonist but does affect the gamma-aminobutyric acid receptor-ionophore complex. GABA-A receptors appear to have at least three allosteric sites at which modulators act: a site at which benzodiazepines act by increasing the opening frequency of gamma-aminobutyric acid-activated chloride channels; a site at which barbiturates act to prolong the duration of channel opening; and a site at which some steroids may act.
ChEBI Ontology
Outgoing Relation(s)
lofendazam (CHEBI:752466) is a benzodiazepine (CHEBI:22720)
INN  Source
lofendazamWHO MedNet