EMBL-EBI | Chemical Biology | ChEBI
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| Formula | HCl.C16H15ClN2 |
| Net Charge | 0 |
| Average Mass | 307.224 |
| Monoisotopic Mass | 306.06905 |
| SMILES | CN1CCN=C(c2ccccc2)c2cc(Cl)ccc21.Cl |
| InChI | InChI=1S/C16H15ClN2.ClH/c1-19-10-9-18-16(12-5-3-2-4-6-12)14-11-13(17)7-8-15(14)19;/h2-8,11H,9-10H2,1H3;1H |
| InChIKey | XBWAZCLHZCFCGK-UHFFFAOYSA-N |
| Roles Classification |
|---|
| Biological Role: | GABA modulator A substance that does not act as agonist or antagonist but does affect the gamma-aminobutyric acid receptor-ionophore complex. GABA-A receptors appear to have at least three allosteric sites at which modulators act: a site at which benzodiazepines act by increasing the opening frequency of gamma-aminobutyric acid-activated chloride channels; a site at which barbiturates act to prolong the duration of channel opening; and a site at which some steroids may act. |
| Application: | GABA modulator A substance that does not act as agonist or antagonist but does affect the gamma-aminobutyric acid receptor-ionophore complex. GABA-A receptors appear to have at least three allosteric sites at which modulators act: a site at which benzodiazepines act by increasing the opening frequency of gamma-aminobutyric acid-activated chloride channels; a site at which barbiturates act to prolong the duration of channel opening; and a site at which some steroids may act. |
| ChEBI Ontology |
|---|
| Outgoing Relation(s) |
| medazepam hydrochloride (CHEBI:752263) is a benzodiazepine (CHEBI:22720) |
| Synonyms | Source |
|---|---|
| Benzodiazepine hydrochloride | ChEMBL |
| NSC-169896 | ChEMBL |
| RO 5-4556 | ChEMBL |
| RO-5-4556 | ChEMBL |