EMBL-EBI | Chemical Biology | ChEBI
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| Formula | C18H13Cl2N3 |
| Net Charge | 0 |
| Average Mass | 342.229 |
| Monoisotopic Mass | 341.04865 |
| SMILES | Cc1ncc2n1-c1ccc(Cl)cc1C(c1ccccc1Cl)=NC2 |
| InChI | InChI=1S/C18H13Cl2N3/c1-11-21-9-13-10-22-18(14-4-2-3-5-16(14)20)15-8-12(19)6-7-17(15)23(11)13/h2-9H,10H2,1H3 |
| InChIKey | CHCISLOJADQUNQ-UHFFFAOYSA-N |
| Roles Classification |
|---|
| Biological Role: | GABA modulator A substance that does not act as agonist or antagonist but does affect the gamma-aminobutyric acid receptor-ionophore complex. GABA-A receptors appear to have at least three allosteric sites at which modulators act: a site at which benzodiazepines act by increasing the opening frequency of gamma-aminobutyric acid-activated chloride channels; a site at which barbiturates act to prolong the duration of channel opening; and a site at which some steroids may act. |
| Application: | GABA modulator A substance that does not act as agonist or antagonist but does affect the gamma-aminobutyric acid receptor-ionophore complex. GABA-A receptors appear to have at least three allosteric sites at which modulators act: a site at which benzodiazepines act by increasing the opening frequency of gamma-aminobutyric acid-activated chloride channels; a site at which barbiturates act to prolong the duration of channel opening; and a site at which some steroids may act. |
| ChEBI Ontology |
|---|
| Outgoing Relation(s) |
| climazolam (CHEBI:750602) is a benzodiazepine (CHEBI:22720) |
| INN | Source |
|---|---|
| climazolam | WHO MedNet |
| Synonym | Source |
|---|---|
| Climasol | ChEMBL |