EMBL-EBI | Chemical Biology | ChEBI
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| ChEBI ID | CHEBI:75044 |
| ChEBI Name | phleomycin |
| Stars | |
| Definition | A mixture of glycopeptide antibiotics originally isolated from the bacterium Streptomyces verticillus whose components all contain a thiazolinylthiazole moiety and can form complexes with redox-active metals such as Co, Cu, and Fe. (Bleomycins are very similar to phleomycins, but have a bithiazole moiety in place of the thiazolinylthiazole moiety). |
| Last Modified | 1 August 2013 |
| Submitter | Gareth Owen |
| Wikipedia |
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| Roles Classification |
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| Biological Roles: | antimicrobial agent A substance that kills or slows the growth of microorganisms, including bacteria, viruses, fungi and protozoans. antibacterial agent A substance (or active part thereof) that kills or slows the growth of bacteria. metabolite Any intermediate or product resulting from metabolism. The term 'metabolite' subsumes the classes commonly known as primary and secondary metabolites. mutagen An agent that increases the frequency of mutations above the normal background level, usually by interacting directly with DNA and causing it damage, including base substitution. |
| Application: | antineoplastic agent A substance that inhibits or prevents the proliferation of neoplasms. |
| ChEBI Ontology |
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| Outgoing Relation(s) |
| phleomycin (CHEBI:75044) has part phleomycin D1 (CHEBI:75046) |
| phleomycin (CHEBI:75044) has role antibacterial agent (CHEBI:33282) |
| phleomycin (CHEBI:75044) has role antimicrobial agent (CHEBI:33281) |
| phleomycin (CHEBI:75044) has role antineoplastic agent (CHEBI:35610) |
| phleomycin (CHEBI:75044) has role metabolite (CHEBI:25212) |
| phleomycin (CHEBI:75044) has role mutagen (CHEBI:25435) |
| phleomycin (CHEBI:75044) is a mixture (CHEBI:60004) |
| Synonym | Source |
|---|---|
| phleomycins | ChEBI |
| Manual Xrefs | Databases |
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| Phleomycin | Wikipedia |
| Citations |
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