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CHEBI:750339 - rg-1530

Default Structure
ChEBI IDCHEBI:750339
ChEBI Namerg-1530
Stars
Last Modified29 June 2026
SubmitterChEMBL
DownloadsMolfile
FormulaC18H14ClFN4O
Net Charge0
Average Mass356.788
Monoisotopic Mass356.08402
SMILESCOc1cc2c(cc1F)C(c1ccccc1Cl)=Nc1c(C)nnc1N2
InChIInChI=1S/C18H14ClFN4O/c1-9-16-18(24-23-9)21-14-8-15(25-2)13(20)7-11(14)17(22-16)10-5-3-4-6-12(10)19/h3-8H,1-2H3,(H2,21,23,24)
InChIKeyUOVCGJXDGOGOCZ-UHFFFAOYSA-N
Roles Classification
Biological Role:
GABA modulator  A substance that does not act as agonist or antagonist but does affect the gamma-aminobutyric acid receptor-ionophore complex. GABA-A receptors appear to have at least three allosteric sites at which modulators act: a site at which benzodiazepines act by increasing the opening frequency of gamma-aminobutyric acid-activated chloride channels; a site at which barbiturates act to prolong the duration of channel opening; and a site at which some steroids may act.
Applications:
antineoplastic agent  A substance that inhibits or prevents the proliferation of neoplasms.
GABA modulator  A substance that does not act as agonist or antagonist but does affect the gamma-aminobutyric acid receptor-ionophore complex. GABA-A receptors appear to have at least three allosteric sites at which modulators act: a site at which benzodiazepines act by increasing the opening frequency of gamma-aminobutyric acid-activated chloride channels; a site at which barbiturates act to prolong the duration of channel opening; and a site at which some steroids may act.
ChEBI Ontology
Outgoing Relation(s)
rg-1530 (CHEBI:750339) has role antineoplastic agent (CHEBI:35610)
rg-1530 (CHEBI:750339) is a benzodiazepine (CHEBI:22720)
Synonyms  Source
R-1530ChEMBL
RG-1530ChEMBL
Citations