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CHEBI:750283 - girisopam
| Formula | C18H17ClN2O2 |
| Net Charge | 0 |
| Average Mass | 328.799 |
| Monoisotopic Mass | 328.09786 |
| SMILES | COc1cc2c(cc1OC)C(c1cccc(Cl)c1)=NN=C(C)C2 |
| InChI | InChI=1S/C18H17ClN2O2/c1-11-7-13-9-16(22-2)17(23-3)10-15(13)18(21-20-11)12-5-4-6-14(19)8-12/h4-6,8-10H,7H2,1-3H3 |
| InChIKey | VQYLGVVODFDFNK-UHFFFAOYSA-N |
| Roles Classification |
|---|
| Biological Role: | GABA modulator A substance that does not act as agonist or antagonist but does affect the gamma-aminobutyric acid receptor-ionophore complex. GABA-A receptors appear to have at least three allosteric sites at which modulators act: a site at which benzodiazepines act by increasing the opening frequency of gamma-aminobutyric acid-activated chloride channels; a site at which barbiturates act to prolong the duration of channel opening; and a site at which some steroids may act. |
| Application: | GABA modulator A substance that does not act as agonist or antagonist but does affect the gamma-aminobutyric acid receptor-ionophore complex. GABA-A receptors appear to have at least three allosteric sites at which modulators act: a site at which benzodiazepines act by increasing the opening frequency of gamma-aminobutyric acid-activated chloride channels; a site at which barbiturates act to prolong the duration of channel opening; and a site at which some steroids may act. |
| ChEBI Ontology |
|---|
| Outgoing Relation(s) |
| girisopam (CHEBI:750283) is a benzodiazepine (CHEBI:22720) |
| INN | Source |
|---|---|
| girisopam | WHO MedNet |
| Synonym | Source |
|---|---|
| NSC-373736 | ChEMBL |
| Citations |
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