EMBL-EBI | Chemical Biology | ChEBI
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| Formula | C16H13ClN2S |
| Net Charge | 0 |
| Average Mass | 300.814 |
| Monoisotopic Mass | 300.04880 |
| SMILES | CN1C(=S)CN=C(c2ccccc2)c2cc(Cl)ccc21 |
| InChI | InChI=1S/C16H13ClN2S/c1-19-14-8-7-12(17)9-13(14)16(18-10-15(19)20)11-5-3-2-4-6-11/h2-9H,10H2,1H3 |
| InChIKey | MWGWTOPCKLQYEU-UHFFFAOYSA-N |
| Roles Classification |
|---|
| Biological Role: | GABA modulator A substance that does not act as agonist or antagonist but does affect the gamma-aminobutyric acid receptor-ionophore complex. GABA-A receptors appear to have at least three allosteric sites at which modulators act: a site at which benzodiazepines act by increasing the opening frequency of gamma-aminobutyric acid-activated chloride channels; a site at which barbiturates act to prolong the duration of channel opening; and a site at which some steroids may act. |
| Application: | GABA modulator A substance that does not act as agonist or antagonist but does affect the gamma-aminobutyric acid receptor-ionophore complex. GABA-A receptors appear to have at least three allosteric sites at which modulators act: a site at which benzodiazepines act by increasing the opening frequency of gamma-aminobutyric acid-activated chloride channels; a site at which barbiturates act to prolong the duration of channel opening; and a site at which some steroids may act. |
| ChEBI Ontology |
|---|
| Outgoing Relation(s) |
| sulazepam (CHEBI:750248) is a benzodiazepine (CHEBI:22720) |
| INN | Source |
|---|---|
| sulazepam | WHO MedNet |
| Synonyms | Source |
|---|---|
| W 3676 | ChEMBL |
| W-3676 | ChEMBL |
| Citations |
|---|