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CHEBI:749883 - demoxepam
| Formula | C15H11ClN2O2 |
| Net Charge | 0 |
| Average Mass | 286.718 |
| Monoisotopic Mass | 286.05091 |
| SMILES | O=C1C[N+]([O-])=C(c2ccccc2)c2cc(Cl)ccc2N1 |
| InChI | InChI=1S/C15H11ClN2O2/c16-11-6-7-13-12(8-11)15(10-4-2-1-3-5-10)18(20)9-14(19)17-13/h1-8H,9H2,(H,17,19) |
| InChIKey | GGRWZBVSUZZMKS-UHFFFAOYSA-N |
| Roles Classification |
|---|
| Biological Role: | GABA modulator A substance that does not act as agonist or antagonist but does affect the gamma-aminobutyric acid receptor-ionophore complex. GABA-A receptors appear to have at least three allosteric sites at which modulators act: a site at which benzodiazepines act by increasing the opening frequency of gamma-aminobutyric acid-activated chloride channels; a site at which barbiturates act to prolong the duration of channel opening; and a site at which some steroids may act. |
| Application: | GABA modulator A substance that does not act as agonist or antagonist but does affect the gamma-aminobutyric acid receptor-ionophore complex. GABA-A receptors appear to have at least three allosteric sites at which modulators act: a site at which benzodiazepines act by increasing the opening frequency of gamma-aminobutyric acid-activated chloride channels; a site at which barbiturates act to prolong the duration of channel opening; and a site at which some steroids may act. |
| ChEBI Ontology |
|---|
| Outgoing Relation(s) |
| demoxepam (CHEBI:749883) is a benzodiazepine (CHEBI:22720) |
| INN | Source |
|---|---|
| demoxepam | WHO MedNet |
| Synonyms | Source |
|---|---|
| Chlordiazepoxide lactam | ChEMBL |
| NSC-169898 | ChEMBL |
| NSC-46007 | ChEMBL |
| NSC-46077 | ChEMBL |
| RO 5-2092 | ChEMBL |
| RO-5-2092 | ChEMBL |
| Citations |
|---|