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CHEBI:749689 - glp-1

Default Structure
ChEBI IDCHEBI:749689
ChEBI Nameglp-1
Stars
Last Modified29 June 2026
SubmitterChEMBL
DownloadsMolfile
FormulaC144H218N38O43
Net Charge0
Average Mass3169.551
Monoisotopic Mass3167.60400
SMILESCC[C@H](C)[C@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](C)NC(=O)[C@H](C)NC(=O)[C@H](CCC(N)=O)NC(=O)CNC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](CO)NC(=O)[C@H](CO)NC(=O)[C@@H](NC(=O)[C@H](CC(=O)O)NC(=O)[C@H](CO)NC(=O)[C@@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](NC(=O)CNC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](C)NC(=O)[C@@H](N)Cc1cncn1)[C@@H](C)O)[C@@H](C)O)C(C)C)C(=O)N[C@@H](C)C(=O)N[C@@H](Cc1cnc2ccccc12)C(=O)N[C@@H](CC(C)C)C(=O)N[C@H](C(=O)N[C@@H](CCCCN)C(=O)NCC(=O)N[C@@H](CCCNC(=N)N)C(=O)O)C(C)C
InChIInChI=1S/C144H218N38O43/c1-17-74(10)115(140(221)161-78(14)121(202)168-101(58-84-61-153-89-36-25-24-35-87(84)89)130(211)170-97(54-71(4)5)131(212)179-113(72(6)7)138(219)167-90(37-26-28-50-145)123(204)154-64-108(191)163-95(143(224)225)39-30-52-152-144(149)150)181-132(213)99(55-81-31-20-18-21-32-81)171-128(209)94(46-49-111(195)196)166-127(208)91(38-27-29-51-146)164-119(200)76(12)158-118(199)75(11)160-126(207)93(44-47-106(148)189)162-107(190)63-156-125(206)96(53-70(2)3)169-129(210)98(57-83-40-42-86(188)43-41-83)172-135(216)103(66-183)175-137(218)105(68-185)176-139(220)114(73(8)9)180-134(215)102(60-112(197)198)173-136(217)104(67-184)177-142(223)117(80(16)187)182-133(214)100(56-82-33-22-19-23-34-82)174-141(222)116(79(15)186)178-109(192)65-155-124(205)92(45-48-110(193)194)165-120(201)77(13)159-122(203)88(147)59-85-62-151-69-157-85/h18-25,31-36,40-43,61-62,69-80,88,90-105,113-117,153,183-188H,17,26-30,37-39,44-60,63-68,145-147H2,1-16H3,(H2,148,189)(H,151,157)(H,154,204)(H,155,205)(H,156,206)(H,158,199)(H,159,203)(H,160,207)(H,161,221)(H,162,190)(H,163,191)(H,164,200)(H,165,201)(H,166,208)(H,167,219)(H,168,202)(H,169,210)(H,170,211)(H,171,209)(H,172,216)(H,173,217)(H,174,222)(H,175,218)(H,176,220)(H,177,223)(H,178,192)(H,179,212)(H,180,215)(H,181,213)(H,182,214)(H,193,194)(H,195,196)(H,197,198)(H,224,225)(H4,149,150,152)/t74-,75-,76-,77-,78-,79+,80+,88-,90-,91-,92-,93-,94-,95-,96-,97-,98-,99-,100-,101-,102-,103-,104-,105-,113-,114-,115-,116-,117-/m0/s1
InChIKeyUCZDWGAJSOUHOU-VDBPWWIZSA-N
Roles Classification
Chemical Role:
Bronsted base  A molecular entity capable of accepting a hydron from a donor (Brønsted acid).
Biological Role:
anti-obesity agent  Any substance which is used to reduce or control weight.
Applications:
hyperglycemic agent  A drug which increases the blood glucose level.
cardiovascular drug  A drug that affects the rate or intensity of cardiac contraction, blood vessel diameter or blood volume.
hypoglycemic agent  A drug which lowers the blood glucose level.
ChEBI Ontology
Outgoing Relation(s)
glp-1 (CHEBI:749689) has role anti-obesity agent (CHEBI:74518)
glp-1 (CHEBI:749689) has role cardiovascular drug (CHEBI:35554)
glp-1 (CHEBI:749689) has role hyperglycemic agent (CHEBI:76916)
glp-1 (CHEBI:749689) has role hypoglycemic agent (CHEBI:35526)
glp-1 (CHEBI:749689) is a polypeptide (CHEBI:15841)
Citations