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CHEBI:749680 - int131
| Formula | C21H12Cl4N2O3S |
| Net Charge | 0 |
| Average Mass | 514.217 |
| Monoisotopic Mass | 511.93227 |
| SMILES | O=S(=O)(Nc1cc(Cl)c(Oc2cnc3ccccc3c2)c(Cl)c1)c1ccc(Cl)cc1Cl |
| InChI | InChI=1S/C21H12Cl4N2O3S/c22-13-5-6-20(16(23)8-13)31(28,29)27-14-9-17(24)21(18(25)10-14)30-15-7-12-3-1-2-4-19(12)26-11-15/h1-11,27H |
| InChIKey | NMRWDFUZLLQSBN-UHFFFAOYSA-N |
| Roles Classification |
|---|
| Biological Role: | immunosuppressive agent An agent that suppresses immune function by one of several mechanisms of action. Classical cytotoxic immunosuppressants act by inhibiting DNA synthesis. Others may act through activation of T-cells or by inhibiting the activation of helper cells. In addition, an immunosuppressive agent is a role played by a compound which is exhibited by a capability to diminish the extent and/or voracity of an immune response. |
| Applications: | immunosuppressive agent An agent that suppresses immune function by one of several mechanisms of action. Classical cytotoxic immunosuppressants act by inhibiting DNA synthesis. Others may act through activation of T-cells or by inhibiting the activation of helper cells. In addition, an immunosuppressive agent is a role played by a compound which is exhibited by a capability to diminish the extent and/or voracity of an immune response. hypoglycemic agent A drug which lowers the blood glucose level. |
| ChEBI Ontology |
|---|
| Outgoing Relation(s) |
| int131 (CHEBI:749680) has role hypoglycemic agent (CHEBI:35526) |
| int131 (CHEBI:749680) has role immunosuppressive agent (CHEBI:35705) |
| int131 (CHEBI:749680) is a aromatic ether (CHEBI:35618) |
| INN | Source |
|---|---|
| ibrigampar | WHO MedNet |
| Synonyms | Source |
|---|---|
| AMG-131 | ChEMBL |
| CHS-131 | ChEMBL |
| Int131 | ChEMBL |
| INT-131 | ChEMBL |
| T-0903131 | ChEMBL |
| T0903131 | ChEMBL |
| Citations |
|---|