EMBL-EBI | Chemical Biology | ChEBI
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| ChEBI ID | CHEBI:749500 |
| ChEBI Name | natalizumab |
| Stars | |
| Last Modified | 29 June 2026 |
| Submitter | ChEMBL |
| Roles Classification |
|---|
| Biological Role: | immunosuppressive agent An agent that suppresses immune function by one of several mechanisms of action. Classical cytotoxic immunosuppressants act by inhibiting DNA synthesis. Others may act through activation of T-cells or by inhibiting the activation of helper cells. In addition, an immunosuppressive agent is a role played by a compound which is exhibited by a capability to diminish the extent and/or voracity of an immune response. |
| Applications: | antineoplastic agent A substance that inhibits or prevents the proliferation of neoplasms. immunosuppressive agent An agent that suppresses immune function by one of several mechanisms of action. Classical cytotoxic immunosuppressants act by inhibiting DNA synthesis. Others may act through activation of T-cells or by inhibiting the activation of helper cells. In addition, an immunosuppressive agent is a role played by a compound which is exhibited by a capability to diminish the extent and/or voracity of an immune response. anti-inflammatory agent Any compound that has anti-inflammatory effects. anti-anaemic agent A compound which increases either the number of red cells or the amount of haemoglobin in the blood. antirheumatic drug A drug used to treat rheumatoid arthritis. antipsychotic agent Antipsychotic drugs are agents that control agitated psychotic behaviour, alleviate acute psychotic states, reduce psychotic symptoms, and exert a quieting effect. |
| ChEBI Ontology |
|---|
| Outgoing Relation(s) |
| natalizumab (CHEBI:749500) has role anti-anaemic agent (CHEBI:75835) |
| natalizumab (CHEBI:749500) has role anti-inflammatory agent (CHEBI:67079) |
| natalizumab (CHEBI:749500) has role antineoplastic agent (CHEBI:35610) |
| natalizumab (CHEBI:749500) has role antipsychotic agent (CHEBI:35476) |
| natalizumab (CHEBI:749500) has role antirheumatic drug (CHEBI:35842) |
| natalizumab (CHEBI:749500) has role immunosuppressive agent (CHEBI:35705) |
| natalizumab (CHEBI:749500) is a organic molecular entity (CHEBI:50860) |
| Synonyms | Source |
|---|---|
| AN100226M | ChEMBL |
| ANTEGRAN | ChEMBL |
| Antegren | ChEMBL |
| Natalizumab | ChEMBL |
| Brand Names | Source |
|---|---|
| Natalizumab elan pharma | ChEMBL |
| Tyruko | ChEMBL |
| Tysabri | ChEMBL |