CHEBI:749500 - natalizumab

ChEBI IDCHEBI:749500
ChEBI Namenatalizumab
Stars
Last Modified29 June 2026
SubmitterChEMBL
Roles Classification
Biological Role:
immunosuppressive agent  An agent that suppresses immune function by one of several mechanisms of action. Classical cytotoxic immunosuppressants act by inhibiting DNA synthesis. Others may act through activation of T-cells or by inhibiting the activation of helper cells. In addition, an immunosuppressive agent is a role played by a compound which is exhibited by a capability to diminish the extent and/or voracity of an immune response.
Applications:
antineoplastic agent  A substance that inhibits or prevents the proliferation of neoplasms.
immunosuppressive agent  An agent that suppresses immune function by one of several mechanisms of action. Classical cytotoxic immunosuppressants act by inhibiting DNA synthesis. Others may act through activation of T-cells or by inhibiting the activation of helper cells. In addition, an immunosuppressive agent is a role played by a compound which is exhibited by a capability to diminish the extent and/or voracity of an immune response.
anti-inflammatory agent  Any compound that has anti-inflammatory effects.
anti-anaemic agent  A compound which increases either the number of red cells or the amount of haemoglobin in the blood.
antirheumatic drug  A drug used to treat rheumatoid arthritis.
antipsychotic agent  Antipsychotic drugs are agents that control agitated psychotic behaviour, alleviate acute psychotic states, reduce psychotic symptoms, and exert a quieting effect.
ChEBI Ontology
Outgoing Relation(s)
natalizumab (CHEBI:749500) has role anti-anaemic agent (CHEBI:75835)
natalizumab (CHEBI:749500) has role anti-inflammatory agent (CHEBI:67079)
natalizumab (CHEBI:749500) has role antineoplastic agent (CHEBI:35610)
natalizumab (CHEBI:749500) has role antipsychotic agent (CHEBI:35476)
natalizumab (CHEBI:749500) has role antirheumatic drug (CHEBI:35842)
natalizumab (CHEBI:749500) has role immunosuppressive agent (CHEBI:35705)
natalizumab (CHEBI:749500) is a organic molecular entity (CHEBI:50860)
Synonyms  Source
AN100226MChEMBL
ANTEGRANChEMBL
AntegrenChEMBL
NatalizumabChEMBL
Brand Names  Source
Natalizumab elan pharmaChEMBL
TyrukoChEMBL
TysabriChEMBL