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CHEBI:748670 - bretazenil
| Formula | C19H20BrN3O3 |
| Net Charge | 0 |
| Average Mass | 418.291 |
| Monoisotopic Mass | 417.06880 |
| SMILES | [H][C@@]12CCCN1C(=O)c1c(Br)cccc1-n1cnc(C(=O)OC(C)(C)C)c12 |
| InChI | InChI=1S/C19H20BrN3O3/c1-19(2,3)26-18(25)15-16-13-8-5-9-22(13)17(24)14-11(20)6-4-7-12(14)23(16)10-21-15/h4,6-7,10,13H,5,8-9H2,1-3H3/t13-/m0/s1 |
| InChIKey | LWUDDYHYYNNIQI-ZDUSSCGKSA-N |
| Roles Classification |
|---|
| Biological Role: | GABA modulator A substance that does not act as agonist or antagonist but does affect the gamma-aminobutyric acid receptor-ionophore complex. GABA-A receptors appear to have at least three allosteric sites at which modulators act: a site at which benzodiazepines act by increasing the opening frequency of gamma-aminobutyric acid-activated chloride channels; a site at which barbiturates act to prolong the duration of channel opening; and a site at which some steroids may act. |
| Application: | GABA modulator A substance that does not act as agonist or antagonist but does affect the gamma-aminobutyric acid receptor-ionophore complex. GABA-A receptors appear to have at least three allosteric sites at which modulators act: a site at which benzodiazepines act by increasing the opening frequency of gamma-aminobutyric acid-activated chloride channels; a site at which barbiturates act to prolong the duration of channel opening; and a site at which some steroids may act. |
| ChEBI Ontology |
|---|
| Outgoing Relation(s) |
| bretazenil (CHEBI:748670) is a benzodiazepine (CHEBI:22720) |
| INN | Source |
|---|---|
| bretazenil | WHO MedNet |
| Synonyms | Source |
|---|---|
| RO 16-6028/000 | ChEMBL |
| RO-166028000 | ChEMBL |
| RO-F61816-6028/000 | ChEMBL |
| Citations |
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