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CHEBI:748477 - netazepide

Default Structure
ChEBI IDCHEBI:748477
ChEBI Namenetazepide
Stars
Last Modified29 June 2026
SubmitterChEMBL
DownloadsMolfile
FormulaC28H30N6O3
Net Charge0
Average Mass498.587
Monoisotopic Mass498.23794
SMILESCNc1cccc(NC(=O)N[C@@H]2N=C(c3ccccn3)c3ccccc3N(CC(=O)C(C)(C)C)C2=O)c1
InChIInChI=1S/C28H30N6O3/c1-28(2,3)23(35)17-34-22-14-6-5-12-20(22)24(21-13-7-8-15-30-21)32-25(26(34)36)33-27(37)31-19-11-9-10-18(16-19)29-4/h5-16,25,29H,17H2,1-4H3,(H2,31,33,37)/t25-/m0/s1
InChIKeyYDZYKNJZCVIKPP-VWLOTQADSA-N
Roles Classification
Biological Role:
GABA modulator  A substance that does not act as agonist or antagonist but does affect the gamma-aminobutyric acid receptor-ionophore complex. GABA-A receptors appear to have at least three allosteric sites at which modulators act: a site at which benzodiazepines act by increasing the opening frequency of gamma-aminobutyric acid-activated chloride channels; a site at which barbiturates act to prolong the duration of channel opening; and a site at which some steroids may act.
Applications:
antineoplastic agent  A substance that inhibits or prevents the proliferation of neoplasms.
GABA modulator  A substance that does not act as agonist or antagonist but does affect the gamma-aminobutyric acid receptor-ionophore complex. GABA-A receptors appear to have at least three allosteric sites at which modulators act: a site at which benzodiazepines act by increasing the opening frequency of gamma-aminobutyric acid-activated chloride channels; a site at which barbiturates act to prolong the duration of channel opening; and a site at which some steroids may act.
ChEBI Ontology
Outgoing Relation(s)
netazepide (CHEBI:748477) has role antineoplastic agent (CHEBI:35610)
netazepide (CHEBI:748477) is a benzodiazepine (CHEBI:22720)
INNs  Source
netazepidaWHO MedNet
netazepideWHO MedNet
Synonyms  Source
SograzepideChEMBL
Yf476ChEMBL
YF-476ChEMBL
Citations