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CHEBI:748280 - tezosentan

Default Structure
ChEBI IDCHEBI:748280
ChEBI Nametezosentan
Stars
Last Modified29 June 2026
SubmitterChEMBL
DownloadsMolfile
FormulaC27H27N9O6S
Net Charge0
Average Mass605.637
Monoisotopic Mass605.18050
SMILESCOc1ccccc1Oc1c(NS(=O)(=O)c2ccc(C(C)C)cn2)nc(-c2ccnc(-c3nnnn3)c2)nc1OCCO
InChIInChI=1S/C27H27N9O6S/c1-16(2)18-8-9-22(29-15-18)43(38,39)34-26-23(42-21-7-5-4-6-20(21)40-3)27(41-13-12-37)31-24(30-26)17-10-11-28-19(14-17)25-32-35-36-33-25/h4-11,14-16,37H,12-13H2,1-3H3,(H,30,31,34)(H,32,33,35,36)
InChIKeyTUYWTLTWNJOZNY-UHFFFAOYSA-N
Roles Classification
Applications:
cardiovascular drug  A drug that affects the rate or intensity of cardiac contraction, blood vessel diameter or blood volume.
antihypertensive agent  Any drug used in the treatment of acute or chronic vascular hypertension regardless of pharmacological mechanism.
ChEBI Ontology
Outgoing Relation(s)
tezosentan (CHEBI:748280) has role antihypertensive agent (CHEBI:35674)
tezosentan (CHEBI:748280) has role cardiovascular drug (CHEBI:35554)
tezosentan (CHEBI:748280) is a aromatic ether (CHEBI:35618)
INN  Source
tezosentanWHO MedNet
Synonyms  Source
ACT-050089ChEMBL
Ro 61-0612ChEMBL
Ro-610612ChEMBL
Brand Name  Source
VeletriChEMBL
Citations