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CHEBI:748280 - tezosentan

Default Structure
ChEBI IDCHEBI:748280
ChEBI Nametezosentan
Stars
Last Modified29 June 2026
SubmitterChEMBL
DownloadsMolfile
FormulaC27H27N9O6S
Net Charge0
Average Mass605.637
Monoisotopic Mass605.18050
SMILESCOc1ccccc1Oc1c(NS(=O)(=O)c2ccc(C(C)C)cn2)nc(-c2ccnc(-c3nnnn3)c2)nc1OCCO
InChIInChI=1S/C27H27N9O6S/c1-16(2)18-8-9-22(29-15-18)43(38,39)34-26-23(42-21-7-5-4-6-20(21)40-3)27(41-13-12-37)31-24(30-26)17-10-11-28-19(14-17)25-32-35-36-33-25/h4-11,14-16,37H,12-13H2,1-3H3,(H,30,31,34)(H,32,33,35,36)
InChIKeyTUYWTLTWNJOZNY-UHFFFAOYSA-N
Roles Classification
Applications:
antihypertensive agent  Any drug used in the treatment of acute or chronic vascular hypertension regardless of pharmacological mechanism.
cardiovascular drug  A drug that affects the rate or intensity of cardiac contraction, blood vessel diameter or blood volume.
ChEBI Ontology
Outgoing Relation(s)
tezosentan (CHEBI:748280) has role antihypertensive agent (CHEBI:35674)
tezosentan (CHEBI:748280) has role cardiovascular drug (CHEBI:35554)
tezosentan (CHEBI:748280) is a aromatic ether (CHEBI:35618)
INN  Source
tezosentanWHO MedNet
Synonyms  Source
ACT-050089ChEMBL
Ro 61-0612ChEMBL
Ro-610612ChEMBL
Brand Name  Source
VeletriChEMBL
Citations