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CHEBI:748271 - tivirapine
| Formula | C16H20ClN3S |
| Net Charge | 0 |
| Average Mass | 321.877 |
| Monoisotopic Mass | 321.10665 |
| SMILES | CC(C)=CCN1Cc2c(Cl)ccc3nc(=S)n(c23)C[C@@H]1C |
| InChI | InChI=1S/C16H20ClN3S/c1-10(2)6-7-19-9-12-13(17)4-5-14-15(12)20(8-11(19)3)16(21)18-14/h4-6,11H,7-9H2,1-3H3,(H,18,21)/t11-/m0/s1 |
| InChIKey | ZNFFMCYSMBXZQU-NSHDSACASA-N |
| Roles Classification |
|---|
| Biological Role: | GABA modulator A substance that does not act as agonist or antagonist but does affect the gamma-aminobutyric acid receptor-ionophore complex. GABA-A receptors appear to have at least three allosteric sites at which modulators act: a site at which benzodiazepines act by increasing the opening frequency of gamma-aminobutyric acid-activated chloride channels; a site at which barbiturates act to prolong the duration of channel opening; and a site at which some steroids may act. |
| Application: | GABA modulator A substance that does not act as agonist or antagonist but does affect the gamma-aminobutyric acid receptor-ionophore complex. GABA-A receptors appear to have at least three allosteric sites at which modulators act: a site at which benzodiazepines act by increasing the opening frequency of gamma-aminobutyric acid-activated chloride channels; a site at which barbiturates act to prolong the duration of channel opening; and a site at which some steroids may act. |
| ChEBI Ontology |
|---|
| Outgoing Relation(s) |
| tivirapine (CHEBI:748271) is a benzodiazepine (CHEBI:22720) |
| INNs | Source |
|---|---|
| tivirapina | WHO MedNet |
| tivirapine | WHO MedNet |
| Synonyms | Source |
|---|---|
| NSC-636661 | ChEMBL |
| R-87027 | ChEMBL |
| Citations |
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