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CHEBI:748253 - dantrolene sodium

Default Structure
ChEBI IDCHEBI:748253
ChEBI Namedantrolene sodium
Stars
Last Modified29 June 2026
SubmitterChEMBL
DownloadsMolfile
FormulaNa.C14H9N4O5
Net Charge0
Average Mass336.239
Monoisotopic Mass336.04706
SMILESO=C1CN(/N=C/c2ccc(-c3ccc([N+](=O)[O-])cc3)o2)C(=O)[N-]1.[Na+]
InChIInChI=1S/C14H10N4O5.Na/c19-13-8-17(14(20)16-13)15-7-11-5-6-12(23-11)9-1-3-10(4-2-9)18(21)22;/h1-7H,8H2,(H,16,19,20);/q;+1/p-1/b15-7+;
InChIKeyKSRLIXGNPXAZHD-HAZZGOGXSA-M
Roles Classification
Biological Role:
immunosuppressive agent  An agent that suppresses immune function by one of several mechanisms of action. Classical cytotoxic immunosuppressants act by inhibiting DNA synthesis. Others may act through activation of T-cells or by inhibiting the activation of helper cells. In addition, an immunosuppressive agent is a role played by a compound which is exhibited by a capability to diminish the extent and/or voracity of an immune response.
Application:
immunosuppressive agent  An agent that suppresses immune function by one of several mechanisms of action. Classical cytotoxic immunosuppressants act by inhibiting DNA synthesis. Others may act through activation of T-cells or by inhibiting the activation of helper cells. In addition, an immunosuppressive agent is a role played by a compound which is exhibited by a capability to diminish the extent and/or voracity of an immune response.
ChEBI Ontology
Outgoing Relation(s)
dantrolene sodium (CHEBI:748253) has role immunosuppressive agent (CHEBI:35705)
dantrolene sodium (CHEBI:748253) is a imidazolidine-2,4-dione (CHEBI:24628)
Synonyms  Source
DantamacrinChEMBL
DantrolenChEMBL
Dantrolene sodium hemiheptahydrateChEMBL
Dantrolene sodium heptahydrateChEMBL
Dantrolene sodium hydrateChEMBL
Dantrolene sodium salt hemiheptahydrateChEMBL
Brand Names  Source
AgilusChEMBL
RevontoChEMBL
RyanodexChEMBL
Citations