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CHEBI:748154 - dolastatin-10

Default Structure
ChEBI IDCHEBI:748154
ChEBI Namedolastatin-10
Stars
Last Modified29 June 2026
SubmitterChEMBL
DownloadsMolfile
FormulaC42H68N6O6S
Net Charge0
Average Mass785.109
Monoisotopic Mass784.49210
SMILES[H][C@@]1([C@H](OC)[C@@H](C)C(=O)N[C@@H](Cc2ccccc2)c2nccs2)CCCN1C(=O)C[C@@H](OC)[C@H]([C@@H](C)CC)N(C)C(=O)[C@@H](NC(=O)[C@H](C(C)C)N(C)C)C(C)C
InChIInChI=1S/C42H68N6O6S/c1-13-28(6)37(47(10)42(52)35(26(2)3)45-40(51)36(27(4)5)46(8)9)33(53-11)25-34(49)48-22-17-20-32(48)38(54-12)29(7)39(50)44-31(41-43-21-23-55-41)24-30-18-15-14-16-19-30/h14-16,18-19,21,23,26-29,31-33,35-38H,13,17,20,22,24-25H2,1-12H3,(H,44,50)(H,45,51)/t28-,29+,31-,32-,33+,35-,36-,37-,38+/m0/s1
InChIKeyOFDNQWIFNXBECV-VFSYNPLYSA-N
Roles Classification
Chemical Role:
Bronsted base  A molecular entity capable of accepting a hydron from a donor (Brønsted acid).
Application:
antineoplastic agent  A substance that inhibits or prevents the proliferation of neoplasms.
ChEBI Ontology
Outgoing Relation(s)
dolastatin-10 (CHEBI:748154) has role antineoplastic agent (CHEBI:35610)
dolastatin-10 (CHEBI:748154) is a peptide (CHEBI:16670)
Synonyms  Source
Dolastatin 10ChEMBL
Dolostatin 10ChEMBL
Citations