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CHEBI:748045 - darusentan

Default Structure
ChEBI IDCHEBI:748045
ChEBI Namedarusentan
Stars
Last Modified29 June 2026
SubmitterChEMBL
DownloadsMolfile
FormulaC22H22N2O6
Net Charge0
Average Mass410.426
Monoisotopic Mass410.14779
SMILESCOc1cc(OC)nc(O[C@H](C(=O)O)C(OC)(c2ccccc2)c2ccccc2)n1
InChIInChI=1S/C22H22N2O6/c1-27-17-14-18(28-2)24-21(23-17)30-19(20(25)26)22(29-3,15-10-6-4-7-11-15)16-12-8-5-9-13-16/h4-14,19H,1-3H3,(H,25,26)/t19-/m1/s1
InChIKeyFEJVSJIALLTFRP-LJQANCHMSA-N
Roles Classification
Application:
antihypertensive agent  Any drug used in the treatment of acute or chronic vascular hypertension regardless of pharmacological mechanism.
ChEBI Ontology
Outgoing Relation(s)
darusentan (CHEBI:748045) has role antihypertensive agent (CHEBI:35674)
darusentan (CHEBI:748045) is a diarylmethane (CHEBI:51614)
INN  Source
darusentanWHO MedNet
Synonyms  Source
HMR-4005ChEMBL
LU-135252ChEMBL
Citations