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CHEBI:747895 - zapnometinib

Default Structure
ChEBI IDCHEBI:747895
ChEBI Namezapnometinib
Stars
DefinitionA selective MEK1/2 inhibitor having potential antiviral activity against HPAIVs (Highly pathogenic avian influenza A viruses).
Last Modified7 July 2026
SubmitterAnneNiknejad
DownloadsMolfile
FormulaC13H7ClF2INO2
Net Charge0
Average Mass409.557
Monoisotopic Mass408.91781
SMILESO=C(O)c1ccc(F)c(F)c1Nc1ccc(I)cc1Cl
InChIInChI=1S/C13H7ClF2INO2/c14-8-5-6(17)1-4-10(8)18-12-7(13(19)20)2-3-9(15)11(12)16/h1-5,18H,(H,19,20)
InChIKeyXCNBGWKQXRQKSA-UHFFFAOYSA-N
Roles Classification
Biological Roles:
anticoronaviral agent  Any antiviral agent which inhibits the activity of coronaviruses.
antiviral agent  A substance that destroys or inhibits replication of viruses.
EC 2.7.11.24 (mitogen-activated protein kinase) inhibitor  An EC 2.7.11.* (protein-serine/threonine kinase) inhibitor that interferes with the action of mitogen-activated protein kinase (EC 2.7.11.24).
ChEBI Ontology
Outgoing Relation(s)
zapnometinib (CHEBI:747895) has role anticoronaviral agent (CHEBI:149553)
zapnometinib (CHEBI:747895) has role antiviral agent (CHEBI:22587)
zapnometinib (CHEBI:747895) has role EC 2.7.11.24 (mitogen-activated protein kinase) inhibitor (CHEBI:79091)
INN  Source
zapnometinibWHO MedNet
Synonyms  Source
Atr 002ChEMBL
ATR-002ChEMBL
ATR002ChEMBL
PD-0184264ChEMBL
Manual XrefsDatabases
D12473KEGG DRUG
DB18244DrugBank
Citations