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CHEBI:747806 - Fimepinostat

Default Structure
ChEBI IDCHEBI:747806
ChEBI NameFimepinostat
Stars
DefinitionAn orally bioavailable inhibitor of both phosphoinositide 3-kinase (PI3K) class I and pan histone deacetylase (HDAC) enzymes, with potential antineoplastic activity. Upon oral administration, fimepinostat inhibits the activity of both PI3K class I isoforms and HDAC, thereby preventing the activation of the PI3K-AKT-mTOR signal transduction pathway that is often overactivated in many cancer cell types.
Last Modified27 May 2026
Submitterjychien
DownloadsMolfile
FormulaC23H24N8O4S
Net Charge0
Average Mass508.564
Monoisotopic Mass508.16412
SMILES[H]ON([H])C(=O)c1c([H])nc(N(C([H])([H])[H])C([H])([H])c2sc3c(N4C([H])([H])C([H])([H])OC([H])([H])C4([H])[H])nc(-c4c([H])nc(OC([H])([H])[H])c([H])c4[H])nc3c2[H])nc1[H]
InChIInChI=1S/C23H24N8O4S/c1-30(23-25-11-15(12-26-23)22(32)29-33)13-16-9-17-19(36-16)21(31-5-7-35-8-6-31)28-20(27-17)14-3-4-18(34-2)24-10-14/h3-4,9-12,33H,5-8,13H2,1-2H3,(H,29,32)
InChIKeyJOWXJLIFIIOYMS-UHFFFAOYSA-N
ChEBI Ontology
Outgoing Relation(s)
Fimepinostat (CHEBI:747806) is a organic molecular entity (CHEBI:50860)
IUPAC Name 
N-hydroxy-2-[[2-(6-methoxy-3-pyridinyl)-4-morpholin-4-ylthieno[3,2-d]pyrimidin-6-yl]methyl-methylamino]pyrimidine-5-carboxamide
Synonyms  Source
CUDC 907PubChem Compound
CUDC-907PubChem Compound
CUDC907PubChem Compound
fimepinostatumPubChem Compound
Registry NumbersSources
CAS:1339928-25-4CAS