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CHEBI:747793 - elafibranor

Default Structure
ChEBI IDCHEBI:747793
ChEBI Nameelafibranor
Stars
DefinitionA dual peroxisome proliferator-activated receptor alpha/delta (PPARα/δ) agonist, used for the treatment of primary biliary cholangitis.
Last Modified7 July 2026
SubmitterAnneNiknejad
DownloadsMolfile
FormulaC22H24O4S
Net Charge0
Average Mass384.497
Monoisotopic Mass384.13953
SMILESCSc1ccc(C(=O)/C=C/c2cc(C)c(OC(C)(C)C(=O)O)c(C)c2)cc1
InChIInChI=1S/C22H24O4S/c1-14-12-16(13-15(2)20(14)26-22(3,4)21(24)25)6-11-19(23)17-7-9-18(27-5)10-8-17/h6-13H,1-5H3,(H,24,25)/b11-6+
InChIKeyAFLFKFHDSCQHOL-IZZDOVSWSA-N
Roles Classification
Biological Roles:
agonist  Substance which binds to cell receptors normally responding to naturally occurring substances and which produces a response of its own.
PPAR modulator  Any compound which acts on the peroxisome proliferator-activated receptor.
Application:
hypoglycemic agent  A drug which lowers the blood glucose level.
ChEBI Ontology
Outgoing Relation(s)
elafibranor (CHEBI:747793) has role agonist (CHEBI:48705)
elafibranor (CHEBI:747793) has role hypoglycemic agent (CHEBI:35526)
elafibranor (CHEBI:747793) has role PPAR modulator (CHEBI:70781)
Synonyms  Source
ElafibranorChEMBL
GFT-505ChEMBL
GFT505ChEMBL
Brand Name  Source
IqirvoWikipedia
Manual XrefsDatabases
D11208KEGG DRUG
DB05187DrugBank
Citations