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CHEBI:747760 - Cyc-116

Default Structure
ChEBI IDCHEBI:747760
ChEBI NameCyc-116
Stars
DefinitionA novel anticancer compound with a unique target profile involving both cell cycle and angiogenesis inhibition mechanisms. In preclinical studies, CYC116 has demonstrated antitumor activity in both solid tumors and hematological cancers.
Last Modified15 May 2026
Submitterjychien
DownloadsMolfile
FormulaC18H20N6OS
Net Charge0
Average Mass368.466
Monoisotopic Mass368.14193
SMILES[H]c1nc(N([H])c2c([H])c([H])c(N3C([H])([H])C([H])([H])OC([H])([H])C3([H])[H])c([H])c2[H])nc(-c2sc(N([H])[H])nc2C([H])([H])[H])c1[H]
InChIInChI=1S/C18H20N6OS/c1-12-16(26-17(19)21-12)15-6-7-20-18(23-15)22-13-2-4-14(5-3-13)24-8-10-25-11-9-24/h2-7H,8-11H2,1H3,(H2,19,21)(H,20,22,23)
InChIKeyGPSZYOIFQZPWEJ-UHFFFAOYSA-N
ChEBI Ontology
Outgoing Relation(s)
Cyc-116 (CHEBI:747760) is a organic molecular entity (CHEBI:50860)
IUPAC Name 
4-methyl-5-[2-(4-morpholin-4-ylanilino)pyrimidin-4-yl]-1,3-thiazol-2-amine
Synonyms  Source
CYC 116PubChem Compound
CYC-116PubChem Compound
CYC116PubChem Compound
YAX4981K2DPubChem Compound
Registry NumbersSources
CAS:693228-63-6CAS