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CHEBI:747632 - eIF4A3-IN-2

Default Structure
ChEBI IDCHEBI:747632
ChEBI NameeIF4A3-IN-2
Stars
DefinitioneIF4A3-IN-2 is a highly selective and noncompetitive eukaryotic initiation factor 4A-3 (eIF4A3) inhibitor with an IC50 of 110 nM.
Last Modified7 May 2026
Submitter
DownloadsMolfile
FormulaC25H19Br2ClN4O2
Net Charge0
Average Mass602.714
Monoisotopic Mass599.95633
SMILESO=C(c1cnn2cc(Br)ccc12)N1CCN(C(=O)c2ccc(Br)cc2)[C@@H](c2ccc(Cl)cc2)C1
InChIInChI=1S/C25H19Br2ClN4O2/c26-18-5-1-17(2-6-18)24(33)31-12-11-30(15-23(31)16-3-8-20(28)9-4-16)25(34)21-13-29-32-14-19(27)7-10-22(21)32/h1-10,13-14,23H,11-12,15H2/t23-/m1/s1
InChIKeyWKKAVTNXNVPCCN-HSZRJFAPSA-N
ChEBI Ontology
Outgoing Relation(s)
eIF4A3-IN-2 (CHEBI:747632) is a organic molecular entity (CHEBI:50860)
Synonym  Source
Eukaryotic Initiation Factor 4A-3 InhibitorCAS
Registry NumbersSources
CAS:2095677-20-4CAS