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CHEBI:747471 - baxdrostat

Default Structure
ChEBI IDCHEBI:747471
ChEBI Namebaxdrostat
Stars
DefinitionA highly selective aldosterone synthase inhibitor (ASI), being investigated as a treatment for hypertension.
Last Modified27 March 2026
SubmitterAnneNiknejad
DownloadsMolfile
FormulaC22H25N3O2
Net Charge0
Average Mass363.461
Monoisotopic Mass363.19468
SMILESCCC(=O)N[C@@H]1CCCc2c(-c3ccc4c(c3)CCC(=O)N4C)cncc21
InChIInChI=1S/C22H25N3O2/c1-3-21(26)24-19-6-4-5-16-17(12-23-13-18(16)19)14-7-9-20-15(11-14)8-10-22(27)25(20)2/h7,9,11-13,19H,3-6,8,10H2,1-2H3,(H,24,26)/t19-/m1/s1
InChIKeyVDEUDSRUMNAXJG-LJQANCHMSA-N
Wikipedia
Roles Classification
Applications:
antihypertensive agent  Any drug used in the treatment of acute or chronic vascular hypertension regardless of pharmacological mechanism.
antiatherosclerotic agent  A cardiovascular drug that prevents atherosclerosis (a disease in which the inside of an artery narrows due to the build up of plaque). Compare with antiatherogenic agent.
ChEBI Ontology
Outgoing Relation(s)
baxdrostat (CHEBI:747471) has role antiatherosclerotic agent (CHEBI:145947)
baxdrostat (CHEBI:747471) has role antihypertensive agent (CHEBI:35674)
baxdrostat (CHEBI:747471) is a organic molecular entity (CHEBI:50860)
Synonyms  Source
BaxdrostatChEMBL
CIN-107ChEMBL
Ro6836191ChEMBL
RO-6836191ChEMBL
Manual XrefsDatabases
BaxdrostatWikipedia
D12789KEGG DRUG
DB19090DrugBank
Registry NumbersSources
CAS:1428652-17-8DrugBank