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CHEBI:747458 - SR8278

ChEBI IDCHEBI:747458
ChEBI NameSR8278
Stars
DefinitionSR8278 is a REV-ERBα antagonist and inhibits the REV-ERBα transcriptional repression activity with an EC50 of 0.47 μM. SR8278 is used to regulate the metabolism in organisms and study biological rhythm. SR8278 also can be used for the research of Duchenne muscular dystrophy and Alzheimer's disease.
Last Modified19 March 2026
Submittercyan
ChEBI Ontology
Outgoing Relation(s)
SR8278 (CHEBI:747458) is a organic molecular entity (CHEBI:50860)
IUPAC Name 
ethyl 2-{[5-(methylsulfanyl)thiophen-2-yl]carbonyl}-1,2,3,4-tetrahydroisoquinoline-3-carboxylate
Registry NumbersSources
CAS:1254944-66-5CAS