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CHEBI:747374 - DPTIP

Default Structure
ChEBI IDCHEBI:747374
ChEBI NameDPTIP
Stars
DefinitionDPTIP is a potent brain penetrant neutral sphingomyelinase 2 (N-SMase 2) inhibitor (exosome inhibitor), with an IC50 of 30 nM.
Last Modified19 February 2026
Submittercyan
DownloadsMolfile
FormulaC21H18N2O3S
Net Charge0
Average Mass378.453
Monoisotopic Mass378.10381
SMILESCOc1cc(-c2nc(-c3ccccc3)c(-c3cccs3)n2)cc(OC)c1O
InChIInChI=1S/C21H18N2O3S/c1-25-15-11-14(12-16(26-2)20(15)24)21-22-18(13-7-4-3-5-8-13)19(23-21)17-9-6-10-27-17/h3-12,24H,1-2H3,(H,22,23)
InChIKeyJMXVHYPSBANVAQ-UHFFFAOYSA-N
ChEBI Ontology
Outgoing Relation(s)
DPTIP (CHEBI:747374) is a organic molecular entity (CHEBI:50860)
Registry NumbersSources
CAS:351353-48-5CAS