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CHEBI:747372 - W23-1006

Default Structure
ChEBI IDCHEBI:747372
ChEBI NameW23-1006
Stars
DefinitionW23-1006 is a selective and covalent ALKBH5 inhibitor. W23-1006 binds to the ALKBH5 C200 residue with an IC50 value of 3.848 μM. W23-1006 shows ~30- and 8-fold stronger inhibitory activity than that against FTO and ALKBH3, respectively. W23-1006 can be used for the study of triple-negative breast cancer.
Last Modified19 February 2026
Submittercyan
DownloadsMolfile
FormulaC17H12BrN3O5
Net Charge0
Average Mass418.203
Monoisotopic Mass416.99603
SMILESCOc1ccc(N2NC(=O)/C(=C\c3cc(Br)cc([N+](=O)[O-])c3)C2=O)cc1
InChIInChI=1S/C17H12BrN3O5/c1-26-14-4-2-12(3-5-14)20-17(23)15(16(22)19-20)8-10-6-11(18)9-13(7-10)21(24)25/h2-9H,1H3,(H,19,22)/b15-8+
InChIKeySJLASDZOGQMHBW-OVCLIPMQSA-N
ChEBI Ontology
Outgoing Relation(s)
W23-1006 (CHEBI:747372) is a organic molecular entity (CHEBI:50860)
Registry NumbersSources
CAS:3035498-92-8CAS