EMBL-EBI | Chemical Biology | ChEBI

Example searches: iron*, InChI=1S/CH4O/c1-2/h2H,1H3, caffeine | Advanced Search

CHEBI:747295 - AA147

Default Structure
ChEBI IDCHEBI:747295
ChEBI NameAA147
Stars
DefinitionAA147 is a endoplasmic reticulum (ER) proteostasis regulator. AA147 promotes protection against oxidative damage in neuronal cells and prevents endothelial barrier dysfunction by activating ATF6 arm (selectively) of the unfolded protein response (UPR) and the NRF2 oxidative stress response. AA147 can rebalances XBP1s expression in vivo, and also induces survival motor neuron (SMN) expression and spinal motorneuron (MN) protection.
Last Modified2 February 2026
Submittercyan
DownloadsMolfile
FormulaC16H17NO2
Net Charge0
Average Mass255.317
Monoisotopic Mass255.12593
SMILESCc1ccc(O)c(NC(=O)CCc2ccccc2)c1
InChIInChI=1S/C16H17NO2/c1-12-7-9-15(18)14(11-12)17-16(19)10-8-13-5-3-2-4-6-13/h2-7,9,11,18H,8,10H2,1H3,(H,17,19)
InChIKeyAWHLTHOHBAGPMY-UHFFFAOYSA-N
ChEBI Ontology
Outgoing Relation(s)
AA147 (CHEBI:747295) is a organic molecular entity (CHEBI:50860)
Registry NumbersSources
CAS:393121-74-9CAS