EMBL-EBI | Chemical Biology | ChEBI
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| ChEBI ID | CHEBI:747183 |
| ChEBI Name | SN-011 |
| Stars | |
| Definition | SN-011 is a potent and selective mouse and human STING inhibitor, with an IC50 of 76 nM for STING signaling. SN-011 competes with cyclic dinucleotide (CDN) for the binding pocket of the STING dimer, blocking CDN binding and STING activation. SN-011 can be used for the research of STING-driven autoimmune and inflammatory disease. |
| Last Modified | 13 January 2026 |
| Submitter | cyan |
| Formula | C25H19FN2O4S |
| Net Charge | 0 |
| Average Mass | 462.502 |
| Monoisotopic Mass | 462.10496 |
| ChEBI Ontology |
|---|
| Outgoing Relation(s) |
| SN-011 (CHEBI:747183) is a organic molecular entity (CHEBI:50860) |
| Registry Numbers | Sources |
|---|---|
| CAS:2249435-90-1 | CAS |